Molecule Day 2006: Acetaminophen

ChemistryThe Chemistry Department hosted ACETAMINOPHEN DAY, the Ninth Annual Interdisciplinary "Molecule Day",which consisted of a student poster session (April 25, 2005). Found in many over-the-counter formulations such as Tylenol®, Anacin® and Excedrin®, acetaminophen is the most widely used pain-reliever/fever reducer. This year is the 50th anniversary of Tylenol hitting the market as the 1st non-aspirin analgesic (originally marketed for children). In 1982, the Tylenol crisis (when several people died from cyanide-laced capsules) resulted in the case being used as a business model for crisis management, the largest media coverage since the assassination of JFK, and major changes in the way over-the-counter medications are manufactured and packaged.

Acetaminophen Day Poster Session

  • Characterization of acetaminophen using IR and NMR
  • Using enzymatic synthesis and kinetic characterization of a catechol metabolite of acetaminophen
  • Acetaminophen hepatotoxicity
  • Acetaminophen vs. NSAIDs (non-steroidal anti-inflammatory drugs)
  • Alcohol-acetaminophen syndrome
  • Dissolution rates of acetaminophen
  • Acetaminophen and asthma: Uncovering the possible link
  • Acetaminophen reducing agent effects on cyclooxygenase
  • Advisory: Risks of acetaminophen use during pregnancy and lactation
  • The metabolism and toxicology of acetaminophen
  • Aspirin vs. acetaminophen: Reye's syndrome and its effects on liver toxicity
  • Synthesis and analysis of acetaminophen derivatives containing a phosphorous atom: A search for the ylide
  • Fever-reducing and pain-relieving, but death-inducing hepatotoxicity from acetaminophen
  • Acetaminophen and hangovers: To treat or not to treat?
  • Automated dissolution of acetaminophen analgesics
  • Protein targets acetaminophen toxicity
  • The synergistic effects of alcohol and acetaminophen on hepatotoxicity
  • Thermodynamics of adsorption: Acetaminophen on activated charcoal
  • The adsorption of acetaminophen on activated charcoal
  • Novel modes of action for acetaminophen
  • Detection of acetaminophen hepatotoxicity by high performance liquid chromatography
  • The effects of complexation of b-cyclodextrin with acetaminophen: An investigation of melting points using differential scanning calorimetry
  • An analysis of dissolution rates of Tylenol® products by HPLC
  • Acetaminophen vs. aspirin (3 General Chemistry posters)
Chemistry Chemistry
Chemistry Chemistry
Students from Muhlenberg
show their work during
the poster session.