Selected Publications and Presentations:
* Denotes a Muhlenberg College student

Enzyme Mechanism and Bacterial Metabolism

• Alexander M. Goldberg*, Miranda K. Robinson*, Erykah S. Starr, Ryan N. Marasco, Alexa C. Alana, C. Skyler Cochrane,  Kameron L. Klugh, David Strzeminski*, Muxue Du*, Keri L. Colabroy, Larryn W. Peterson “L-DOPA dioxygenase activity on 6-substituted dopamine analogs” Biochemistry 60, no. 32 (2021): 2492-2507.
• Colabroy, K., Bell, J.K. Lab eNotebooks. Biochemistry Education: From Theory to Practice. 1337, 173–195, doi: 10.1021/bk-2019-1337.ch008 (2019).
• Colabroy, Keri L., Alyssa D. Horwitz*, Victoria R. Basciano*, Yizhi Fu*, Kelly M. Travitz*, Miranda K. Robinson*, Brittany A. Shimanski*, and Thomas W. Hoffmann*. “A New Way of Belonging: Active-Site Investigation of L-DOPA Dioxygenase, a VOC Family Enzyme from Lincomycin Biosynthesis.” Biochemistry 58, no. 48 (December 3, 2019): 4794–98. https://doi.org/10.1021/acs.biochem.9b00456.
• Wang, Yifan, Inchul Shin, Yizhi Fu*, Keri L. Colabroy, and Aimin Liu. “Crystal Structures of L-DOPA Dioxygenase from Streptomyces Sclerotialus.” Biochemistry, June 10, 2019. https://doi.org/10.1021/acs.biochem.9b00396.
• Wang, Yifan, Ian Davis, Inchul Shin, Daniel J. Wherritt, Wendell P. Griffith, Kednerlin Dornevil, Keri L. Colabroy, and Aimin Liu. “Biocatalytic Carbon–Hydrogen and Carbon–Fluorine Bond Cleavage through Hydroxylation Promoted by a Histidyl-Ligated Heme Enzyme.” ACS Catalysis 9, no. 6 (June 7, 2019): 4764–76. https://doi.org/10.1021/acscatal.9b00231.
• Colabroy, K.L., Mayer, K*. Benchtop Immobilized Metal Affinity Chromatography, Reconstitution and Assay of a Polyhistidine Tagged Metalloenzyme for the Undergraduate Laboratory. Journal of Visualized. Exeriments. (138), e58012, doi:10.3791/58012 (2018)
• Colabroy, KL Tearing down to build up: Metalloenzymes in the biosynthesis lincomycin, hormaomycin and the pyrrolo[1,4]benzodiazepines,   Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics (2016); 1864 (6), 724-737
• Colabroy, KL, *Smith, IR, *Vlahos, AHS, *Markham, AJ, *Jakubik, ME. Defining a kinetic mechanism for l-DOPA 2,3 dioxygenase, a single-domain type I extradiol dioxygenase from Streptomyces lincolnensis Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, (2014); 1844 (3) 607-14.
• Connor, KL; Colabroy, KL; Gerratana, BA. Heme Peroxidase with a functional role as an L-Tyrosine Hydroxylase in the Biosynthesis of Anthramycin. Biochemistry  (2011); 50 (41) 8926-36
• Colabroy KL, *Hackett WT, *Markham AJ, *Rosenberg J, *Cohen DE, Jacobson A. Biochemical characterization of L-DOPA 2,3-dioxygenase, a single-domain type I extradiol dioxygenase from lincomycin biosynthesis. Arch Biochem Biophys (2008); 479 (2) 131-8
• Colabroy, KL and Begley, TP. Tryptophan catabolism: identification and characterization of a new degradative pathway. Journal of Bacteriology (2005); 187 (22) 7866-9 
• Colabroy, KL, *Smith, IR; *Dunn, BR; *Gassaway, E; *Vlahos, AHS; *Sholevar, R. (Muhlenberg); Liu, A and Dornevil, K (Georgia State University) The Enzymology of Propylhygric Acid Assembly- EPR studies on tyrosine hydroxylase, a homology model for LmbB1 – an extradiol dioxygenase, and evidence for activity of LmbX – a protein of unknown function. Enzymes, Coenzymes and Metabolic Pathways Gordon Research Conference, 2014
• Colabroy, KL, *Florio, T; *Hoffmann, T; *Sticco; M; *Smith IR; *Gassaway, E. (Muhlenberg); Liu, A and Dornevil, K (Georgia State University). The Enzymology of Propylhygric Acid Assembly: EPR studies on tyrosine hydroxylase and sequence similarity networks for LmbB1 – a VOC extradiol dioxygenase. Enzymes, Coenzymes and Metabolic Pathways Gordon Research Conference, 2016
• Colabroy, KL, Smith, IR; *Gassaway, E;  *Vlahos, AHS; *Hoffmann, T; *Florio, T. (Muhlenberg); Liu, A and Dornevil, K (Georgia State University). The Enzymology of Propylhygric Acid Assembly: Mass Spectrometry of the LmbX reaction and Kinetic study of L-DOPA dioxygenase.  Enzymes, Coenzymes and Metabolic Pathways Gordon Research Conference, 2017.
• Colabroy, KL; *Juliano, B; *Fu, Y; *Gassaway, E; *Zimmerman, ZE. Progress toward the chemical characterization 3-vinyl-2,3-pyrroline-5-carboxylic acid (VPCA): A bacterial, natural-product synthon (BIOL 78) a poster presentation in the Current Topics in Biochemistry session at the  254th American Chemical Society National Meeting in Washington, DC, August 20-24, 2017.
• Colabroy KL and Brock Juliano*. CMS Assisted Identification of Small-Molecule Bacterial Metabolites using  ESI with direct injection a lecture in the workshop entitled Mass Spectrometry for Chemists – Direct Analysis of TLC Plates, Solids, Liquids and Gases hosted by Advion, Inc. at the American Chemical Society Meeting in Washington, DC.  

Teaching and Learning

• Colabroy, KL. A Writing Intensive Methods-Based Laboratory Course for Undergraduates Biochemistry and Molecular Biology Education (2011) 39 (3) 196-203. 
• Colabroy, KL and Provost, J. Teaching a broad non-science major audience using the science of food and cooking (2016), at the 251st American Chemical Society National Meeting, Chemical Education Division, Integration of STEM and the Liberal Arts session – presentation. 
• Colabroy, KL. Integrating Enzymology into course-associated labs. Establishing and Expanding Teaching-Research Networks, (2013) NSF-WIDER workshop. Birmingham, AL.
• Provost, JJ; Colabroy, KL; Kelly, BS; and Wallert, MA. The Science of Cooking: Understanding the Biology and Chemistry Behind Food and Cooking, First Edition. © 2016 John Wiley & Sons, Inc.  
• Colabroy, KL. Integrating Undergraduate Research into the Curriculum, at the Beginning a Research Program in the Natural Sciences at a Predominantly Undergraduate Institution workshop by the Council for Undergraduate Research, Presenter and Facilitator, Denver, CO (2016)
• Colabroy, KL. An LVAIC instructional video archive of research and teaching laboratory instrumentation for use in courses and undergraduate research, Teagle Blended Learning Project, DeSales University, Center Valley, PA  (2016)