Identifying Sequence Conservation

The ClustalW database is part of the EMBL European Bioinformatics Institute Webpage. This program allows you to align different sequences in order to identify regions of homology between proteins. Any proteins can be compared to one another. For example, proteins with similar functions in different species or proteins from the same family in a single species can be compared in order to find homologous sequences.

Click on the link below to access the sequences you will be comparing. When the screen opens, first select the "Select All" and then "Copy" commands under the Edit menu. Then use your browsers back button to return to the Clustal W search page. Use the "Paste" option under the edit menu to paste the beta-globin sequences into the search box.

Click on the link below to access ClustalW

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